Celsis In Vitro Technologies File Library

Celsis In Vitro Technologies Product Industry Brochure General information about the products offered by Celsis In Vitro Technologies.

Hepatocyte Brochure Information about Celsis In Vitro Technologies hepatocyte offerings.

InVitroCYP Microsome Brochure General information about the InVitroCYP microsomes offered by Celsis In Vitro Technologies.

Celsis Development Services Industry Brochure General information about Celsis Development Services and the service offerings.

Celsis IVT Hepatocyte Users Workshop May registration form

In Vitro Technologies Reference List Journal articles and book chapters written by current and former IVT employees. Revised 24 May 2006

The One Stop September 2007

Poster - Cryopreserved Fish Hepatocytes as a Model For Bio-accumulation and Cytotoxicity Evaluation of Aquatic Pollutants Poster was presented at the 2007 SOT Annual Meeting that was held in Charlotte, North Carolina.

Poster - Human In Vitro Models of Dermal Metabolism Poster that was presented at the 2007 SOT Annual Meeting in Charlotte, North Carolina.

Poster: Effects of InVitroGold on Selected CYP Enzyme Activity Levels and Cellular Apoptosis and Via The poster entitled, Effects of InVitroGold on Selected CYP Enzyme Activity Levels and Cellular Apoptosis and Viability in Human Hepatocytes, was presented at the ISSX 2006 meeting in Puerto Rico.

Poster - Clearance Studies using LiverPool(TM) Hepatocytes Presented at the 9th European ISSX Meeting 2006 in Manchester, U.K.

Poster: Chemically-Induced Apoptosis in Freshly-I424 Poster presented at the SOT 2006 Annual Meeting in San Diego, California.

Poster: Comparison of Halo- and Nitro-benzene Toxicity in Rat and Human Hepatocytes Poster presented at the SOT 2006 Annual Meeting in San Diego, California.

Poster: In Vitro Replication of HCV from Clinical Isolates, in Cryo Human Hepatocytes Presented at the HEP DART 2005 meeting in Big Island, HI.

Poster - Comparison of Human and Cynomolgus Monkey Hepatocyte CYP450 Levels in Induction Studies Presented at the 2005 Annual AAPS Meeting in Nashville, TN.

Poster - Human Hepatocytes: An Untapped Resource for Functional Genomic Studies of CYP450 Enzymes Presented at the 2004 Annual AAPS Meeting in Baltimore, Maryland.

Poster - Comparison of Fresh and Cryo Cyno Monkey Hepatocyte CYP450 Levels in Induction Studies Presented at the 2005 ISSX/JSSX Meeting in Maui, Hawaii.

Poster - Metabolic Stability and Clearance of Pharmaceutical Compounds in Pre-Pooled Cryopreserved Hepatocytes Presented at the 2005 ISSX/JSSX Meeting in Maui, Hawaii.

Poster - Prediction of Hepatic Clearance Using Cryopreserved Hepatocytes Presented at PharmSciFair 2005 in Nice, France.

Poster - Use of Plateable Cryopreserved Rat Hepatocytes as a Model to Assess Hepatotoxicity and Drug Presented at the 2005 Society of Toxicology Annual Meeting in New Orleans, Louisiana.

Poster: Drug- or Metabolite-Induced Apoptosis in Plateable Cryopreserved Human Hepatocytes Presented at the SBS 10th Annual Conference and Exhibition, September 2004, Orlando, FL.

Poster: Evaluation of Chemically-Induced Apoptosis in Rat and Human Hepatocytes Presented at the 7th International ISSX Meeting in Vancouver, Canada.

Poster: Determination of Apoptosis in Plateable Cryopreserved Human Hepatocytes Presented at the 2004 Society of Toxicology Meeting in Baltimore, MD.

Poster: Evaluation of Long-term Toxicity Studies using Plateable Cryopreserved Human Hepatocytes Presented at the AAPS Annual Meeting in Salt Lake City, Utah, October 26-30, 2003.

Poster: Identification of Glutathione Conjugates of Troglitazone in Human Hepatocytes Presented at the 11th North American ISSX meeting in Orlando, Florida October 27-31, 2002.

Poster: Phenacetin as a Marker in Evaluation of CYP1A2 Induction in Human Hepatocytes Presented at 12th North American ISSX Meeting in Providence, Rhode Island October 12-16, 2003.

Poster: Cytotoxicity of Troglitazone vs. Rosiglitazone in Cryopreserved Human Hepatocytes. Presented at the AAPS Annual Meeting and Exposition, October 2001, Denver, Colorado.

Poster: Induction Potential of INN 00835 in Rat and Human Hepatocytes. Presented at the AAPS Annual Meeting and Exposition, October 2001, Denver, Colorado.

Poster: The effects of P450 Inhibitors on INN 00835 in Human Hepatocytes. Presented at the 6th International ISSX Meeting, October 2001, Munich, Germany.

Poster: High Throughput Screening for Drug Toxicity. Presented at the SBS Conference 2001, Baltimore, Maryland.

Poster: A High Throughput Screening Assay for Hepatotoxicity Using Cryopreserved Human Hepatocytes. Presented at the SBS 6th Annual Conference and Exhibition, September, 2000, Vancouver, British Columbia, Canada.

Poster: Protein Binding and Drug Metabolism. Presented at the AAPS Annual Meeting and Exposition, October 2000, Indianapolis, Indiana.

Poster: Effects of Cryopreservation on P450 Oxidation and Phase II Conjugation Activities. Presented at the AAPS Annual Meeting and Exposition, October 2000, Indianapolis, Indiana.

Poster: Effects of Organic Solvents. Presented at the AAPS Annual Meeting and Exposition, October 2000, Indianapolis, Indiana.

Poster: 3-Day Caco-2 Culture for In Vitro Intestinal Permeability Screening. Presented at the SBS 6th Annual Conference and Exhibition, September 2000, Vancouver, British Columbia, Canada.

Product Literature - Plateable Crypreserved Human Hepatocytes General Information about In Vitro Technologies Plateable Cryopreserved Human Hepatocytes.

Product Literature- Custom-Cell Products General information about the custom product offerings from Celsis In Vitro Technologies.

Product Literature - Fresh human and animal hepatocytes General information about Celsis In Vitro Technologies fresh human and animal hepatocytes.

Product Literature - Animal and Human Cryopreserved Hepatocytes General information about Celsis In Vitro Technologies human and animal cryopreserved hepatocytes.

Product Literature- LiverPool 5-, 10-, and 20-donor cryopreserved human hepatocytes General information about Celsis In Vitro Technologies LiverPool 5-, 10-, and 20- Donor Pooled Cryopreserved Human Hepatocytes.

Product Literature - InVitroGRO Hepatocyte Media General information about Celsis In Vitro Technologies InVitroGRO hepatocyte media.

Product Literature - Dermal Absorption Studies General information about Dermal Absorption Studies offered by Celsis Development Services.

Product Literature - CYP Pathway Identification Studies General information about CYP Pathway Identification Studies offered by Celsis Development Services.

Product Literature - Metabolic Stability General information about Metabolic Stability Studies offered by Celsis Development Services.

Product Literature - Metabolic Profiling and Metabolite Identification Studies General information about Metabolic Profiling and Metabolite Identification Studies offered by Celsis Development Services.

Product Literature - Ex Vivo Studies General information about Ex Vivo Studies offered by Celsis Development Services.

Product Literature - Protein Binding Studies General information about Protein Binding Studies offered by Celsis Development Services.

Product Literature - Dermal Metabolism General information about Dermal Metabolism studies offered by Celsis Development Services

Product Literature - Cytotoxicity Studies General information about Cytotoxicity Studies offered by Celsis Development Services.

Product Literature - Cytochrome P450 Inhibition Studies General information about Cytochrome P450 Inhibition Studies offered by Celsis Development Services.

Product Literature - Cytochrome P450 Induction Studies General information about Cytochrome P450 Induction Studies offered by Celsis Development Services

Product Literature - Absorption Studies General information about Absorption Studies offered by Celsis Development Services

Protocol - Cultured Hepatocyte Induction Assay An assay for performing induction studies using plated hepatocytes. Revised 01 March 2006

Protocol - Caco-2 Transport Assays Instructions on how to use Caco-2 assay kits for transport studies and transport kinetic assays.

Protocol - Plating Fresh Hepatocyte Suspensions Instructions on how to plate fresh hepatocyte suspensions from In Vitro Technologies.

Protocol - Cultured Hepatocyte Xenobiotic Metabolism Assay An assay for performing metabolism studies using plated hepatocytes.

Protocol - Cultured Hepatocyte Toxicity Assay An assay for performing toxicity studies using plated hepatocytes. Revised 10 April 2003

Protocol - Cryopreserved Hepatocyte MTT Cytotoxicity Assay An assay for studying cytotoxicity using MTT as a marker of cell viability. Revised 02 May 2001

Protocol - Cryopreserved Hepatocyte Drug Metabolism Assay An assay to evaluate the metabolism of test articles using cryopreserved human hepatocytes. Revised 29 October 2002

Protocol - Cryopreserved Hepatocyte Metabolic Stability Assay for a 96-Well Plate An assay for studying the metabolic stability of test articles using human hepatocytes.

Protocol - Cryopreserved Hepatocyte ATP Cytotoxicity Assay for a 96-Well Plate An assay for determining cytotoxicity using ATP as a marker of cell viability.

Protocol - Cryopreserved Hepatocyte ATP Cytotoxicity Assay for a 384-Well Plate An assay for determining cytotoxicity using ATP as a marker of cell viability

Technical Sheet - InVitroCYP H-class Microsomes General instructions for use on how to use InVitroCYP H-class Microsomes.

Technical Sheet - InVitroCYP M-class Microsomes General instructions on how to use InVitroCYP M-class microsomes.

Technical Sheet - Plateable Cryopreserved Hepatocytes Instructions on how to thaw and plate plateable cryopreserved human and animal hepatocytes.

Technical Sheet - Fresh Animal and Human Hepatocyte Suspensions Instructions on how to use fresh hepatocyte suspensions from Celsis In Vitro Technologies

Technical Sheet - Fresh Plated Animal and Human Hepatocytes Instructions on how to unpack and use fresh plated hepatocytes from Celsis In Vitro Technologies.

Technical Sheet - Human and Animal Cryopreserved Hepatocytes Instructions on how to thaw Celsis In Vitro Technologies cryopreserved hepatocytes.

Technical Sheet - LiverPool 5-, 10-, and 20-donor pooled cryopreserved human hepatocytes Instructions on how to use In Vitro Technologies LiverPool 5-, 10, 20-donor pooled cryopreserved human hepatocytes.

Technical Sheet - InVitroGRO KHB General information on InVitroGRO KHB. For use with In Vitro Technologies cryopreserved hepatocytes.

Technical Sheet - Torpedo Antibiotic Mix The Torpedo Antibiotic Mix is added to any of Celsis IVT's InVitroGRO hepatocyte medium.

Technical Sheet - InVitroGRO HI Medium InVitroGRO HI Medium is an incubation medium used when culturing hepatocytes.

Technical Sheet - InVitroGRO HT Medium InVitroGRO HT Medium is a thawing medium used to thaw cryopreserved hepatocytes.

Technical Sheet - InVitroGRO CP Medium InVitroGRO CP Medium is a plating medium used with IVT's plateable cryopreserved hepatocytes.

Technical Sheet - Human and Animal S9 Instructions on the use of liver S9 fractions to study drug/chemical metabolism.

Technical Sheet - Animal Liver Microsomes Instructions on the use of liver microsomes to study drug/chemical metabolism.

Technical Sheet - Lung, Intestine, and Kidney Microsomes Instructions on the use of lung, intestine, and kidney microsomes to study drug/chemical metabolism.

Technical Sheet - Human Renal Proximal Tubule Cells Instructions on the use of IVT's Human Renal Proximal Tubule Cells.

Technical Sheet - InVitroGRO PT Medium InVitroGRO PT Medium is used with IVT's Human Renal Proximal Tubule Cells.

Technical Sheet - InVitroFREEZE Cryopreservation Medium Instructions on the use of In Vitro Technologies InVitroFREEZE cryopreservation medium.